Brammall was born in Canberra.[2] He was born with the rare genetic disorder prune belly syndrome and his doctors did not think he would survive. He underwent several operations and spent quite a lot of time in and out of hospital during the first 10 years of his life.　　Patrick Brammall graduated from VCA in 2001.[4] His breakthrough role was in the 2004 television movie The Alice, which led to a starring role in the spin-off series in 2005. He also had a starring role in television series Canal Road in 2008. This was followed by many roles in television series, short films and theatre.[5]　　In 2010, he played Griff's brother Tim in the gentle comedy Griff the Invisible.　　In 2012, Brammall had a starring role in two ABC comedy series – The Strange Calls as Sgt Neil Lloyd, and A Moody Christmas as Sean Moody (for which he won the AACTA Award for Best Performance in a Television Comedy). In 2013, Brammall reprised the role of Sean Moody for the eight-part series, The Moodys. He also wrote episode 5 of the series, and was consequently nominated for an Australian Writers' Guild award for Best Narrative Comedy.　　In 2013 he acted in The Elegant Gentleman's Guide to Knife Fighting, a sketch comedy show for the ABC, before going on to play Rupert Murdoch in the Nine Network miniseries, Power Games: The Packer-Murdoch War, which went to air in September 2013.　　Brammall also has a starring role in the ABC comedy series Upper Middle Bogan as Danny Bright, which premiered in August 2013. The second season premiered in October 2014.　　In 2014, Brammall joined the main cast of the Network Ten series Offspring, playing the role of midwife Leo Taylor. He also has a co-starring role in the Josh Lawson written and directed comedy feature, The Little Death.　　In 2015, he starred in both the film Ruben Guthrie and the Stan series No Activity.　　Brammall first met his future wife Samantha Nield on the set of TV series The Alice, where she was a member of the crew. The couple eventually marr